Dept. of Biomedical Science

최수영
  • Field

    Biochemistry

  • Name

    Korean Choi, Soo Young

  • Title

    Professor

  • Office

    The Department of Biomedical Science, The College of Natural Sciences 8409

  • Tel

    033-248-2112

  • email

Educational background

1986 University of Tennessee, Knoxville, U.S.A (Ph.D-Biochemistry)

1982 Yonsei University (Master of Science - Biochemistry)

1980 Yonsei University (Bachelor of Science - Biochemistry)

Major careers

2015 ~ Present ; Chief Review Board of KRF(Korea Research Foundation)

2015 ~ Present ; Member of Council for National Bioscience and Bioengineering Strategy

2015 ~ Present Member of Basic Planning Committee for National Bioscience and Bioengineering

2014 ~ President of the Korean Society for Biochemistry and Molecular Biology

2013 ~ Present Chairman of Gangwon Convention &Visitors Bureau

2007 ~ 2010, 2012 – 2014 Vice President of Hallym University

2010 ~ President of the Korean Society for Brain and Neural Science

2006 ~ Present Member of The Korean Academy of Science and Technology

2006 ~ 2010 Chief Editor of the BMB Reports

2003 ~ 2007 Provost for Academic and Research Affairs of Hallym University

2002 ~ 2013 Board of the Chuncheon Bioindustry Foundation

2002 ~ 2003 Director of Industry-Academia Cooperation, Hallym University

1998 ~ 1999 Dean of planning, Hallym University

1994 ~ 1996 Vice Dean of Academic Affairs, Hallym University

1987 ~ 1988 Post-doctoral Fellow, University of California, Berkeley, U.S.A

Studies & Books

■ Theses(2012-2017)
- H.Y.Jung, D.W.Kim, H.J.Kwon, D.Y.Yoo, I.K.Hwang, M.H.Won, T.G.Cho, S.Y.Choi, S.M.Moon 
SUMO-1 does not protect against, but delays the neuronal damage in the spinal cord after ischemia/reperfusion. Molecular Medicine Reports In press (2017)
- D.Y.Yoo, D.W.Kim, H.J.Kwon, H.Y.Jung, S.M.Nam, J.W.Kim, J.Y.Chung, M.H.Won, Y.S.Yoon, S.Y.Choi, I.K.Hwang
Chronic administration of SUMO-1 has negative effects on novel object recognition memory as well as cell proliferation and neuroblast differentiation in the mouse dentate gyrus. Molecular Medicine Reports In press (2017)
- Expressions of G proteins, p-GATA4 and VEGF in hearts of transgenic mice overexpressing β1 and β2 adrenergic receptors. Molecular Medicine Reports In press (2017)
- J.H.Ahn, M.C.Shin, J.H.Park, I.H.Kim, J.H.Cho, T.K.Lee, J.C.Lee, B.H.Chen, B.N.Shin, H.J.Tae, J.Park, S.Y.Choi, Y.L.Lee, D.W.Kim, M.H.Won, J.H.Cho, M.H.Won
Effects of long-term post-ischemic treadmill exercise on gliosis in the aged gerbil hippocampus induced by transient cerebral ischemia. Molecular Medicine Reports In Press (2017)
- J.C.Lee, H.J.Tae, I.H.Kim, J.H.Cho, T.K.Lee, J.H.Park, J.H.Ahn, S.Y.Choi, B.H.Chen, B.N.Shin, G.S.Cho, D.W.Kim, I.J.Kang, Y.G.Kwon, Y.M.Kim, M.H.Won, E.J.Bae
Roles of HIF-1α, VEGF and NF-κB in ischemic preconditioning-mediated neuroprotection of hippocampal CA1 pyramidal neurons against a subsequent transient cerebral ischemia. Molecular Neurobiology In Press (2017)
- J.H.Ahn, S.k.Hong, H.J.Tae, J.Park, S.Y.Choi, J.H.Park, I.H.Kim, J.H.Cho, T.K.Lee, J.C.Lee, B.H.Chen, B.N.Shin, Y.L.Lee, Y.M.Kim, M.H.Won, E.J.Bae
Immunoreactivities of calbindin-D28k, calretinin and parvalbumin in the somatosensory cortex of rodents during normal aging. Journal of Molecular Neuroscience In Press (2017)
- Neuroprotection and reduced gliosis by pre- and post-treatments of hydroquinone in a gerbil model of transient cerebral ischemiaJournal of Chemico-Biological Interactions In Press (2017)
- Lee, S.J. Kang, H.K. Eum, W.S. Park, J. Choi, S.Y. Kwon, H.Y.
Tat-biliverdin reductase A protects INS-1 cells from human islet amyloid polypeptide-induced cytotoxicity by alleviating oxidative stress and ER stress. Cell Biology International In Press (2017)
- E.A.Kim, J.M.Na, J.Kim, S.Y.Choi, J.Y.Ahn and S.W.Cho
Neuroprotective effect of 3-(naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride on brain ischaemia/reperfusion injury. Journal of Neuroimmune Pharmacology In Press (2017)
- J.H.Park, Y.H.Kim, J.H.Ahn, S.Y.Choi, S.k.Hong, S.K.kim, I.J.Kang, Y.M.Kim, T.K.Lee, M.H.Won, C.H.Lee
Atomoxetine protects against NMDA receptor-mediated hippocampal neuronal death following transient global cerebral ischemia. Current Neurovascular Research In Press (2017)
- Atomoxetine protects against NMDA receptor-mediated hippocampal neuronal death following transient global cerebral ischemia Current Neurovascular Research In Press (2017)
- J.Kim, C.H.Cho, H.G.Hahn, S.Y.Choi and S.W.Cho
Neuroprotective effects of N-adamantyl-4-methylthiazol-2-amine against amyloid β-induced oxidative stress in mouse hippocampus. Brain Research Bulletin 128, 22-28 (2017)
- H.S.Jo, D.W.Kim, M.J.Shin, S.B.Cho, J.H.Park, C.H.Lee, E.J.Yeo, Y.J.Choi, H.J.Yeo, E.J.Sohn, O.Son, S.W.Cho, D.S.Kim, Y.H.Yu, K.W.Lee, J.Park, W.S.Eum, S.Y.Choi
Tat-HSP22 inhibits oxidative stress-induced hippocampal neuronal cell death by regulation of the mitochondrial pathway. Molecular Brain 10, 1-13 (2017)
- S.Y.An, G.S.Youn, H.Kim, S.Y.Choi and J.Park
Celastrol suppresses expression of adhesion molecules and chemokines by inhibiting JNK-STAT1/NF-kB activation in poly(I:C)-stimulated astrocytes. BMB reports 50, 25-30 (2017)
- H.S.Jo, E.J.Yeo, M.J.Shin, Y.J.Choi, H.J.Yeo, S.B.Cho, J.H.Park, C.H.Lee, W.S.Eum, S.Y.Choi
Tat-DJ-1 enhances cell survival by inhibition of oxidative stress, NF-κB and MAPK activation in HepG2 cells. Biotechnology Letters 39, 511-521 (2017)
- E.A.Kim, C.H.Cho, S.Y.Choi, J.Y.Ahn, S.J.Yang, and S.W.Cho
2-Cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride alters lipopolysaccharide-induced proinflammatory cytokines and neuronal morphology in mouse fetal brain. Neuropharmacology 102, 32-41 (2016)
- H.J.Kim, G.S.Youn, S.Y.An, H.Y.Kwon, S.Y.Choi, J.Park
2,3-dimethoxy-2′-hydroxychalcone ameliorates TNF-α-induced ICAM-1 expression and subsequent monocyte adhesiveness via NF-kappaB inhibition and HO-1 induction in HaCaT cells. BMB Reports 49(1), 57-62 (2016)
- S.H.Park, M.J.Shin, D.W.Kim, J.Park, S.Y.Choi, and Y.H.Kang
Blockade of monocyte-endothelial trafficking by transduced tat-superoxide dismutase protein. International Journal of Molecular Medicine 37, 387-397 (2016)
- N.K.Yu, H.F.Kim, J.Shim, S.Kim, D.W.Kim, C.Kwak, S.E.Sim, J.H.Choi, S.Ahn, J.Yoo, S.L.Choi, D.J.Jang, C.S.Lim, C.Kang, S.Y.Choi and B.K.Kaang
A transducible nuclear/nucleolar protein, mLLP, regulates neuronal morphogenesis and synaptic transmission. Scientific Reports 6(Article number:22892), 1-11 (2016)
- H.Y.Jung, D.W.Kim, H.S.Yim, D.Y.Yoo, J.W.Kim, M.H.Won, Y.S.Yoon, S.Y.Choi and I.K.Hwang
Heme Oxygenase-1 protects neurons from ischemic damage by upregulating expression of Cu,Zn-superoxide dismutase, catalase, and brain-derived neurotrophic factor in the rabbit spinal cord. Neurochemical Research 41, 869-879 (2016)
- C.H.Cho, E.A.Kim, J.Kim, S.Y.Choi, S.J.Yang and S.W.Cho
N-Adamantyl-4-methylthiazol-2-amine suppresses amyloid β-induced neuronal oxidative damage in cortical neurons Free Radical Research 50(6), 678-690 (2016)
- G.S.Youn, K.W.Lee, S.Y.Choi and J.Park
Overexpression of HDAC6 induces pro-inflammatory responses by regulating ROS-MAPK-NF-kB/AP-1 signalling pathways in macrophages. Free Radical Biology &Medicine 97, 14-23 (2016)
- H.S.Jo, H.J.Yeo, H.J.Cha, S.J.Kim, S.B.Cho, J.H.Park, C.H.Lee, E.J.Yeo, Y.J.Choi, W.S.Eum, S.Y.Choi
Transduced Tat-DJ-1 protein inhibits cytokines-induced pancreatic RINm5F cell death. BMB Reports 49(5), 297-302 (2016)
- J.H.Ahn, B.H.Chen, B.N.Shin, T.K.Lee, J.H.Cho, I.H.Kim, J.H.Park, J.C.Lee, H.J.Tae, C.H. Lee, M.H.Won, Y.L.Lee, S.Y.Choi, S.k.Hong
Comparison of catalase immunoreactivity in the hippocampus between young, adult and aged mice and rats. Molecular Medicine Reports 14(1), 851-856 (2016)
- E.H.Ahn, D.W.Kim, M.J.Shin, E.J.Ryu, J.I.Yong, S.Y.Chung, H.J.Cha, S.J.Kim, Y.J.Choi, D.S.Kim, S.W.Cho, K.Lee, Y.S.Cho, H.Y.Kwon, J.Park, W.S.Eum, S.Y.Choi
Tat-ATOX1 inhibits streptozotocin (STZ)-induced pancreatic RINm5F cell death and attenuates diabetes in a mice model International Journal of Molecular Medicine 38(1), 217-224 (2016)
- E.J.Sohn, M.J.Shin, W.S.Eum, D.W.Kim, J.I.Yong, E.J.Ryu, J.H.Park, S.B.Cho, H.J.Cha, S.J.Kim, H.J.Yeo, E.J.Yeo, Y.J.Choi, S.K.Im, H.Y.Kweon, D.S.Kim, Y.H.Yu, S.W.Cho, M.Park, J.Park, Y.J.Cho, S.Y.Choi
Tat-NOL3 protects against oxidative stress-induced hippocampal neuronal cell death by regulation of apoptotic pathways. International Journal of Molecular Medicine 38(1), 225-235 (2016)
- M.J.Shin, D.W.Kim, H.S.Jo, S.B.Cho, J.H.Park, C.H.Lee, E.J.Yeo, Y.J.Choi, J.A.Kim, J.S.Hwang, E.J.Sohn, J.H.Jeong, D.S.Kim, H.Y.Kwon, Y.J.Cho, K.Lee, K.H.Han, J.Park, W.S.Eum, S.Y.Choi
Tat-PRAS40 prevent hippocampal HT-22 cell death and oxidative stress induced animal brain ischemic insults. Free Radical Biology &Medicine 97, 250-262 (2016)
- A.R.Goh, G.S.Youn, K.Y.Yoo, M.H.Won, S.Z.Han, S.S.Lim, K.W.Lee, S.Y.Choi and J.Park
Aronia melanocarpa concentrate ameliorates pro-inflammatory responses in HaCaT karatinocytes and 12-O-tetradecanoylphorbol-13-acetate-induced ear edema in mice. Journal of Medicinal Food 19, 654-662 (2016)
- E.J.Sohn, M.J.Shin, D.W.Kim, O.Son, H.S.Jo, S.B.Cho, J.H.Park, C.H.Lee, E.J.Yeo, Y.J.Choi, Y.H.Yu, D.S.Kim, S.W.Cho, O.S.Kwon, Y.J.Cho, J.Park, W.S.Eum, S.Y.Choi
PEP-1-GSTpi protein enhanced hippocampal neuronal cell survival after oxidative damage. BMB Reports 49, 382-387 (2016)
- S.M.Park, C.W.Park, T.K.Lee, J.H.Cho, J.H.Park, J.C.Lee, B.H.Chen, B.N.Shin, J.H.Ahn, H.J.Tae, M.C.Shin, T.G.Ohk, J.H.Cho, M.H.Won, S.Y.Choi, I.H.Kim
Effect of ischemic preconditioning on antioxidant status in the gerbil hippocampal CA1 region after transient forebrain ischemia. Neural Regeneration Research 11, 1081-1089 (2016)
- J.H.Ahn, J.H.Choi, J.H.Park, I.H.Kim, J.H.Cho, J.C.Lee, H.M.Koo, G.Hwangbo, K.Y.Yoo, C.H.Lee, I.K.Hwang, J.H.Cho, S.Y.Choi, Y.G.Kwon, Y.M.Kim, I.J.Kamng and M.H.Won
Long-term exercise improves memory deficits via restoration and microvessel damage, and enhancement of neurogenesis in the aged gerbil hippocampus after ischemic stroke. Neurorehabilitation &Neural Repair 30, 894-905 (2016)
- S.M.Yu, H.J.Yeo, S.Y.Choi and S.J Kim
Cytokine-induced apoptosis inhibitor-1 causes dedifferentiation of rabbit articular chondrocytes via the ERK-1/2 and p38 kinase pathways. The International Journal of Biochemistry &Cell Biology 80, 10-18 (2016)
- S.H.Eo, S.Y.Choi and S.J.Song
PEP-1-SIRT2-induced matrix metalloproteinase-1 and -13 modulates type II collagen expression via ERK signaling in rabbit articular chondrocytes. Experimental Cell Research 348, 201-208 (2016)
- H.S.Jo, H.J.Cha, S.J.Kim, H.J.Yeo, S.B.Cho, J.H.Park, C.H.Lee, E.J.Yeo, Y.J.Choi, W.S.Eum, S.Y.Choi
Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation. Medicinal Chemistry Research 25, 2589-2598 (2016)
- D.Y.Yoo, D.W.Kim, J.Y.Chung, H.Y.Jung, J.W.Kim, Y.S.Yoon, I.K.Hwang, G.M.Choi, S.Y. Choi and S.M.Moon
Cu,Zn-Superoxide Dismutase Increases the Therapeutic Potential of Adipose-derived Mesenchymal Stem Cells by Maintaining Antioxidant Enzyme Levels. Neurochemical
Research 41, 3300-3307 (2016)
- H.S.Jo, D.S.Kim, E.H.Ahn, D.W.Kim, M.J.Shin, S.B.Cho, J.H.Park, C.H.Lee, E.J.Yeo, Y.J.Choi, H. J. Yeo, C.S.Y.Chung, S.W.Cho, K.H.Han, J.Park, W.S.Eum, S.Y.Choi
Protective effects of Tat-NQO1 against oxidative stress-induced HT-22 cell damage and ischemic injury in an animal model. BMB reports 49, 617-622 (2016)
- J.H.Ahn, B.H.Chen, B.N.Shin, J.H.Cho, I.H.Kim, J.H.Park, J.C.Lee, H.J.Tae, Y.L.Lee, J.Lee, K.Byun, G.B.Jeong, B.Lee, S.U.Kim, Y.M.Kim, M.H.Won and S.Y.Choi
Intravenously infused F3.Olig2 improve memory deficits via restoring demyelination in the aged hippocampus following experimental ischemic stroke. Cell Transplantation 25, 2129-2144 (2016)
- D.Y.Yoo, D.W.Kim, M.J.Kim, J.H.Choi, H.Y.Jung, S.M.Nam, J.W.Kim, Y.S.Yoon, S.Y.Choi and I.K.Hwang
Sodium butyrate, a histone deacetylase Inhibitor, ameliorates SIRT2-induced memory impairment, reduction of cell proliferation, and neuroblast differentiation in the dentate gyrus. Neurological Research 37, 69-76 (2015)
- H.R.Kim, D.W.Kim, H.S.Jo, S.B.Cho, J.H.Park, C.H.Lee, Y.J.Choi, E.J.Yeo, S.Y.Park, S.T.Kim, Y.H.Yu, D.S.Kim, H.AKim, S.W.Cho, K.H.Han, J.Park, W.S.Eum and S.Y.Choi
Tat-Biliverdin reductase A inhibits inflammatory response by regulation of MAPK and NF-kB pathways in Raw 264.7 cells and edema mouse model. Molecular Immunology 63, 355-366 (2015)
- J.C.Lee, B.H.Chen, J.H.Cho, I.H.Kim, J.H.Ahn, J.H.Park, H.J.Tae, G.S.Cho, B.C.Yan, D.W.Kim, I.K.Hwang, J.Park, Y.L.Lee, S.Y.Choi and M.H.Won
Changes in the expression of DNA-binding/differentiation protein inhibitors in neurons and glial cells of the gerbil hippocampus following transient global cerebral ischemia. Molecular Medicine Reports 11, 2477-2485 (2015)
- D.W.Kim, S.H.Lee, S.K.Ku, J.E.Lee, H.J.Cha, J.K.Youn, H.Y.Kwon, J.H.Park, E.Y.Park, S.W.Cho, K.H.Han, J.Park, W.S.Eum, S.Y.Choi
The effects of PEP-1-FK506BP on dry eye disease in a rat model. BMB Reports 48, 151-156 (2015)
- S.M.Ju, G.S.Youn, Y.S.Cho, S.Y.Choi, J.Park
Celastrol ameliorates cytokine toxicity and pro-inflammatory immune responses via suppression of NF-κB activation in the RINm5F beta cells. BMB Reports 48, 172-177 (2015)
- J.C.Lee, H.J.Tae, G.S.Cho, J.H.Cho, I.H.Kim, J.H.Ahn, J.H.Park, B.H.Chen, B.N.Shin, J.H.Cho, J.Park, Y.M.Kim, S.Y.Choi and M.H.Won
Ischemic preconditioning protects neurons and maintains immunoreactivity of kynurenic acid in the gerbil hippocampal CA1 region following transient cerebral ischemia. International Journal of Molecular Medicine 35, 1537-1544 (2015)
- E.A.Kim, C.H.Cho, D.W.Kim, S.Y.Choi, J.W.Huh, and S.W.Cho
Antioxidative effects of ethyl 2-(3-(benzo[d]thiazol-2-yl)ureido)acetate against amyloid β-induced oxidative cell death via NF-κB, GSK-3β, and β-catenin signaling pathways in cultured cortical neurons. Free Radical Research 49, 411-421 (2015)
- S.J.Lee, H.K.Kang, D.K.Song, W.S.Eum, J.Park, S.Y.Choi, H.Y.Kwon
Transduction of PEP-1-heme oxygenase-1 into insulin-producing INS-1 cells protects them against cytokine-induced cell death. Biochemical Biophysical Research Communication 461, 549-554 (2015)
- E.J.Bae, B.H.Chen, B.N.Shin, J.H.Cho, I.H.Kim, J.H.Park, J.C.Lee, H.J.Tae, S.Y.Choi, J.D.Kim, Y.L.Lee, M.H.Won and J.H.Ahn
Comparison of immunoreactivities of calbindin-D28k, calretinin and paralbumin in the striatum between young and aged mice, rats and gerbils. Neurochemical Research 40, 864-872 (2015)
- S.M.Kim, I.K.Hwang, D.Y.Yoo, W.S.Eum, D.W.Kim, M.J.Shin, E.H.Ahn, H.S.Jo, E.J.Ryu, J.I.Yong, S.W.Cho, O.S.Kwon, K.W.Lee, Y.S.Cho, K.H.Han, J.Park, S.Y.Choi
Tat-antioxidant 1 protects against stress-induced hippocampal HT-22 cells death and attenuate ischemic insult in animal model. Journal of Cellular and Molecular Medicine 19, 1333-1345 (2015)
- Y.N.Kim, D.W.Kim, H.S.Jo, M.J.Shin, E.H.Ahn, E.J.Ryu, J.I.Yong, H.J.Cha, S.J.Kim, H.J.Yeo, J.K.Youn, J.H.Hwang, J.H.Jeong, D.S.Kim, S.W.Cho, J.Park, W.S.Eum, S.Y.Choi
Tat-CBR1 inhibits inflammatory responses through the suppressions of NF-kB and MAPKs activation in macrophages and mice. Toxicology and Applied Pharmacology 286, 124-134 (2015)
- M.J.Kim, M.Park, D.W.Kim, M.J.Shin, O.Son, H.S.Jo, H.J.Yeo, S.B.Cho, J.H.Park, C.H.Lee, D.S.Kim, O.S.Kwon, J.Kim, K.H.Han, J.Park, W.S.Eum, S.Y.Choi
Transduced PEP-1-PON1 proteins regulate microglial activation and dopaminergic neuronal death in a Parkinson’s disease model. Biomaterials 64, 45-56 (2015)
- S.A.Eom, D.W.Kim, M.J.Shin, E.H.Ahn, S.Y.Chung, E.J.Sohn, H.S.Jo, S.J.Jeon, D.S.Kim, H.Y.Kwon, S.W.Cho, K.H.Han, J.Park, W.S.Eum, S.Y.Choi
Protective effects of PEP-1-Catalase on stress-induced cellular toxicity and MPTP-induced Parkinson’s disease. BMB Reports 48, 395-400 (2015)
- H.S.Hwang, I.YPark, D.W.Kim, S.Y.Choi and H.AKim
PEP-1-FK506BP12 inhibits matrix metalloproteinase expression in human articular chondrocytes and in a mouse carrageenan-induced arthritis model. BMB Reports 48, 407-412 (2015)
- Y.Park, H.Kim, L.Park, D.Min, J.Park, S.Choi, M.H.Park
Effective delivery of endogenous antioxidants ameliorates diabetic nephropathy PLoS One 10(6), e0130815 (2015)
- W.Y.Seo, G.S.Youn, S.Y.Choi and J.Park
Butein, a tetrahydroxychalcone, supresses pro-inflammatory responses in HaCaT karatinocytes. BMB Reports 48, 495-500 (2015)
- E.S.Lee, H.J.Seo, S.S.Back, S.H.Han, Y.J.Jeong, J.W.Lee, S.Y.Choi and K.H.Han
Transcriptional regulation of Niemann-Pick C1 like 1(NPC1L1) gene by liver receptor homolog-1 (LRH-1). BMB Reports 48, 513-518 (2015)
- K.S.Yoon, S.M.Ju, S.Y.Choi and J.Park
HDAC6 mediates HIV-1 Tat-induced pro-inflammatory responses by regulating MAPK-NF-kappaB/AP-1 pathways in astrocytes. Glia 63(11), 1953-1965 (2015)
- S.J.Woo, M.J.Shin, D.W.Kim, H.S.Jo, J.Yong, E.J.Ryu, H.J.Cha, S.J.Kim, H.J.Yeo, S.B.Cho, J.H.Park, C.H.Lee, E.J.Yeo, Y.J.Choi, S.Park, S.K.Im, D.S.Kim, O.S.Kwon, J.Park, W.S.Eum, and S.Y.Choi
Effects of low doses of Tat-PIM2 protein against hippocampal neuronal cell survival. Journal of Neurological Science 358, 226-235 (2015)
- S.Hong, J.Y.Ahn, G.S.Cho, I.H.Kim, J.H.Cho, J.H.Ahn, J.H.Park, M.H.Won, B.H.Chen, B.N.Shin, H.J.Tae, S.M.Park, J.H.Cho, S.Y.Choi and J.C.Lee
Monocarboxylate transporter 4 plays a significant role in the neuroprotective mechanism of ischemic preconditioning in transient cerebral ischemia. Neural Regeneration Research 10, 1604-1611 (2015)
- J.C.Lee, H.J.Tae, B.H.Chen, J.H.Cho, I.H.Kim, J.H.Ahn, J.H.Park, B.N.Shin, H.Y.Lee, Y.S.Choe, J.H.Cho, S.Hong, S.Y.Choi, M.H.Won, C.W.Park
Failure in neuroprotection of remote limb ischemic postconditioning in the hippocampus of a gerbil model of transient cerebral ischemia. Journal of the Neurological Sciences 358, 377-384 (2015)
- E.A.Kim, C.H.Cho, J.Kim, H.G.Hahn, S.Y.Choi, S.J.Yang, and S.W.Cho
The azetidine derivative, KHG26792 protects against ATP-induced activation of NFAT and MAPK pathways through P2X7 receptor in microglia. Neurotoxicology 51, 198-206 (2015)
- D.W.Kim, S.H.Lee, M.J.Shin, K.Kim, S.K.Ku, J.K.Youn, S.B. Cho, J.H.Park, C.H.Lee, O.Son, E.J.Sohn, S.W.Cho, J.H.Park, H.AKim, K.H.Han, J.Park, W.S.Eum, S.Y.Choi
PEP-1-FK506BP inhibits alkali burn-induced corneal inflammation on the rat model of corneal alkali injury. BMB Reports 48, 618-623 (2015)
- S.H.Eo, D.W.Kim, S.Y.Choi, H.A.Kim, S.J.Kim
PEP-1-SIRT2 causes dedifferentiation and COX-2 expression via the MAPK pathways in rabbit articular chondrocytes. Experimental Cell Research 339, 351-359 (2015)
- Alessandro Matte, Luigia De Falco, Achille Iolascon, Narla Mohandas, Xiuli An, Angela Siciliano, Christophe Leboeuf, Anne Janin, Mariasole Bruno, Soo Young Choi, Dae Won Kim, and Lucia De Franceschi
The interplay between peroxyredoxin-2 and Nrf2 is important in limiting oxidative mediated dysfunction in β-thalassemic erythropoiesis. Antioxidants and Redox Signaling 23(16) 1284-1297 (2015)
- M.J.Shin, D.W.Kim, Y.P.Lee, E.H.Ahn, H.S.Jo, D.S.Kim, O.S.Kwon, T.C.Kang, Y.J.Cho, J.Park, W.S.Eum and S.Y.Choi
Tat-glyoxalase protein inhibits against ischemic neuronal cell damage and ameliorates ischemic injury. Free Radical Biology &Medicine 67, 195-210 (2014)
- W.Kim, D.W.Kim, H.J.Jeong, D.Y.Yoo, H.Y.Jung, S.M.Nam, J.H.Kim, J.H.Choi, M.H.Won, Y.S.Yoon, S.M.Moon, S.Y.Choi, I.K.Hwang
Tat-DJ-1 Protects Neurons from Ischemic Damage in the Ventral Horn of Rabbit Spinal Cord via Increasing Antioxidant Levels. Neurochemical Research 39, 187-193 (2014)
- M.J.Kim, H.J.Jeong, D.W.Kim, E.J.Sohn, H.S.Jo, D.S.Kim, H.A.Kim, E.Y.Park, J.H.Park, O.Son, K.H.Han, J.Park, W.S.Eum, S.Y.Choi
PEP-1-PON1 protein regulates inflammatory response in Raw 264.7 macrophages and ameliorates TPA-induced animal model. PLoS One 9(1), e86034 (2014)
- Y.N.Kim, H.Y.Jung, W.S.Eum, D.W.Kim, M.J.Shin, E.H.Ahn, S.J. Kim, C.H.Lee, J.I.Yong, E.J.Ryu, J.Park, J.H.Choi, I.K.Hwang and S.Y.Choi
Neuroprotective effects of PEP-1-carbonyl reductase 1 (CBR1) against oxidative stress-induced ischemic neuronal cell damage. Free Radical Biology &Medicine 69, 181-196 (2014)
- E.J.Sohn, M.J.Shin, D.W.Kim, E.H.Ahn, H.S.Jo, D.S.Kim, S.W.Cho, K.H.Han, J.Park, W.S.Eum, H.S.Hwang, S.Y.Choi
Tat-fused recombinant human SAG prevents dopaminergic neurodegeneration in a MPTP-induced Parkinson’s disease model. Molecules and Cells 37, 226-233 (2014)
- E.Y. Park, B.H.Kim, E.J.Lee, E.S.Chang, D.W.Kim, S.Y. Choi and J.H.Park
Targeting of receptor for advanced glycation end products suppresses cyst growth in polycystic kidney disease. Journal of Biological Chemistry 289, 9254-9262 (2014)
372. E.H.Ahn, D.W.Kim, M.J.Shin, H.R.Kim, S.M.Kim, S.J.Woo, S.A.Eom,D.S.Kim, S.W.Cho, J.Park, W.S.Eum and S.Y.Choi
PEP-1-PEA-15 protects against toxin-induced neuronal damage in a mouse model of Parkinson’s disease. Biochimica Biophysica Acta (General Subject) 1840, 1686-1700 (2014)
- Seung-Ju Yang , Woo Je Lee, Eun-A Kim, Kee Dal Nam, Hoh-Gyu Hahn, Soo Young Choi, Sung-Woo Cho
Effects of N-adamantyl-4-methylthiazol-2-amine on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats. European Journal of Pharmacology 736, 26-34 (2014)
- H.J.Jeong, D.Y.Yoo, D.W.Kim, H.J.Yeo, S.B.Cho, J.Hyeon, J.H.Jung, J.Park, W.S.Eum, H.S.Hwang, M.H.Won, I.K.Hwang and S.Y.Choi
Neuroprotective effect of PEP-1-peroxiredoxin2 on CA1 regions in the hippocampus against ischemic insult. Biochimica Biophysica Acta (General Subject) 1840, 2321-2330 (2014)
- Meeyoung Park, Ehud Ohana, Soo Young Choi, Myeong-Sok Lee, Jong Hoon Park, and Shmuel Muall
Multiple Roles of the SO42-/Cl-/OH-exchangerSlc26a2inChondrocytefunctions.Journal of Biological Chemistry 289, 1993-2001 (2014)
- S.Y.Park, M.H.Kim, J.H.Ahn, S.J.Lee, J.H.Lee, W.S.Eum, S.Y.Choi and H.Y.Kwon
The stimulatory effect of fatty acids on glucose uptake involves both Akt and AMPK activation in C2C12 skeletal muscle cells. Krean Journal of Phisiology and Pharmacology 18, 255-261 (2014)
- Eun-A Kim, A Reum Han, Jiyoung Choi, Jee-Yin Ahn, Soo Young Choi, and Sung-Woo Cho
Anti-inflammatory mechanisms of N-adamantyl-4-methylthiazol-2-amine in lipopolysaccharide-stimulated BV-2 microglial cells. International Immunopharmacology 22, 73-83 (2014)
- D.J.Kwon, Y.S.Bae, S.M.Ju, G.S.Youn, S.Y.Choi and J.Park
Salicortin suppresses lipopolysaccharide-stimulated inflammatory responses via blockade of NF-<kappa>B activation in RAW 264.7 macrophages. BMB Reports 47, 318-323 (2014)
- E.J.Lee, S.A.song, H.W.Mun, K.H.Yoo, S.Y.Choi, E.Y.Park and J.H.Park
Blockage of Interleukin-8 receptor signaling inhibits cyst development in vitro, via suppression of cell proliferation in autosomal polycystic kidney disease. Nephrology 19, 471-478 (2014)
- Eun-A Kim, Jiyoung Choi, A Reum Han, Chang Hun Cho, Soo Young Choi, Jee-Yin Ahn, and Sung-Woo Cho
2-Cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride inhibits microglial activation by suppression of nuclear factor-kappa B and mitogen-activated protein kinase signaling. Journal of Neuroimmune Pharmacology 9, 461-467 (2014)
- J.C.Lee, J.H.Cho, G.S.Cho, J.H.Ahn, J.H.Park, I.H.Kim, J.H.Cho, H.J.Tae, S.H.Cheon, J.Y.Ahn, J.Park, S.Y.Choi and M.H.Won
Effect of transient cerebral ischemia on the expression of receptor for advanced glycation end products (RAGE). Neurochemical Research 39, 1553-1563 (2014)
- S.J.Lee, J.D.Yoo, S.Y.Choi and O.S.Kwon
The expression and secretion of vimentin in the progression of non-alchoholic steatohepatitis. BMB Reports 47, 457-462 (2014)
- Eun-A Kim, Chang Hun Cho, Hoh-Gyu Hahn, Soo Young Choi, and Sung-Woo Cho
2-Cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride protects against beta-amyloid-induced activation of the apoptotic cascade in cultured cortical neurons. Cellular and Molecular Neurobiology 34, 963-972 (2014)
- Gi Soo Youn, Dong-Joo Kwon, Sung Mi Ju, Hyangshuk Rhim, Yong Soo Bae, Soo Young Choi and Jinseu Park
Celastrol ameliorates HIV-1 Tat-induced inflammatory responses via NF-kappaB and AP-1 inhibition and HO-1 induction in astrocytes. Toxicology and Applied Pharmacology 280, 42-52 (2014)
- H.J.Tae, J.H.Park, J.H.Cho, I.H.Kim, J.H.Ahn, J.C.Lee, J.D.Kim, J.Park, S.Y.Choi, M.H.Won
Oenanthe javanica extract increases immunoreactivities of antioxidant enzymes in the rat kidney. Chinese Medical Journal 127, 3758-3763 (2014)
- M.J.Chae, D.W.Kim, Y.J.Kim, H.Y.Kweon, Y.J.Cho, S.Y.Choi and H.R.Lee
Toxicity assessment of a novel silk fibroin and poly-methyl-methacrylate composite material. Molecular and Cellular Toxicology 10, 277-283 (2014)
- J.K.Youn, D.W.Kim, S.T.Kim, S.Y.Park, E.J.Yeo, Y.J.Choi, H.R.Lee, D.S.Kim, S.W. Cho, K.H.Han, J.Park, W.S.Eum, H.S.Hwang, S.YChoi
PEP-1-HO-1 prevents MPTP-induced degeneration of dopaminergic neurons in Parkinson’s disease mouse model. BMB Reports 47, 569-574 (2014)
- H.J.Jeong, M.Y.Park, D.W.Kim, E.J.Ryu, J.I.Yong, H.J.Cha, S.J.Kim, H.J.Yeo, J.H.Jeong, D.S.Kim, H.C.Kim, E.J.Shin, E.Y.Park, J.H.Park, H.Y.Kwon, J.Park, W.S.Eum and S.Y.Choi
Downregulation of MAPK/NF-κB signaling underlies anti-inflammatory response induced by transduced PEP-1-Prx2 proteins in LPS-induced Raw 264.7 and TPA-induced mouse ear edema model. International Immunopharmacology 23, 426-433 (2014)
- E.H.Ahn, D.W.Kim, M.J.Shin, Y.N.Kim, H.R.Kim, S.J.Woo, S.M.Kim, D.S. Kim, J.Kim, J.Park, W.S.Eum, H.S.Hwang, S.Y.Choi
PEP-1-ribosomal protein S3 protects dopaminergic neurons in MPTP-induced Parkinson’s disease mouse model. Free Radical Biology &Medicine 55, 36-45 (2013)
- M.J.Kim, D.W.Kim, B.R.Lee, M.J. Shin, Y.N.Kim, S.A.Eom, B.J.Park, Y.S.Cho, K.H. Han, J.Park, H.S.Hwang, W.S.Eum, S.Y.Choi
Transduced Tat-Glyoxalase protein attenuates streptozotocin-induced diabetes in a mouse model. Biochemical Biophysical Research Communication 430, 294-300 (2013)
- S.R.Jung, N.J.Song, D.K.Yang, Y.J.Cho, B.J.Kim, J.W.Hong, U.J.Yun, D.G.Jo, Y.M.Lee, S.Y.Choi and K.W.Park
Silk proteins stimulate osteoblast differentiation by suppressing the Notch signaling pathway in mesenchymal stem cells. Nutrition Research 33, 162-170 (2013)
I.G.Kyeong, W.S.Eum, S.Y.Choi and J.H.Kang
Oxidative modification of neurofilament-L and neuronal cell death induced by the catechol neurotoxin, tetrahydropapaveroline. Toxicology Letter 217, 59-66 (2013)
- J.H.Ahn, M.H.Kim, H.J.Kwon, S.Y.Choi and H.Y.Kwon
Protective effects of oleic acid against palmitic acid-induced apoptosis in pancreatic AR42J cells and its mechanism. Korean Journal of Physiology and Pharmacology 17, 43-50 (2013)
- Sujin Lee , Jeong Han Kang, Soo Young Choi, Ki Tae Suk, Dong Joon Kim, Oh-Shin Kwon
PKCδ as a regulator for TGFβ1-induced α-SMA production in a murine nonalcoholic steatohepatitis model. PLoS One 8(2): e55979 (2012)
- D.W.Kim, S.H.Lee, S.K.Ku, S.H.Cho, S.W.Cho, G.H.Yoon, H.S.Hwang, J.Park, W.S.Eum, O.S.Kwon and S.Y.Choi
Transduced PEP-1-FK506BP ameliorates corneal injury in Botulium toxin A-induced dry eye mouse model. BMB Reports 46, 124-129 (2013)
- W.S.Eum, K.J.Lee, D.W.Kim, S.S.Lim, I.J.Kang, J.Park and S.Y.Choi
Anti-Inflammatory effects of extracts from Caesalpinia sappan L. on skin inflammation. Journal of Korean Society Food Science and Nutrition 42, 384-388 (2013)
- S.H.Lee, J.K.Kim, D.W.Kim, H.S.Hwang, W.S.Eum, J.Park, K.H.Han, J.S.Oh, S.Y.Choi
Antitumor activity of methyl gallate by inhibition of focal adhesion formation and Akt phosphorylation in glioma cells. Biochimica Biophysica Acta (General Subject) 1830, 4017-4029 (2013)
- Kim JE, Kim DS, Ryu HJ, Kim WI, Kim MJ, Kim DW, Choi SY, Kang TC.
The effect of P2X7 receptor activation on nuclear factor-kappa B phosphorylation induced by status epilepticus in the rat hippocampus. Hippocampus. 23, 500-514 (2013)
- Su Sun Back, Jinsu Kim, Daehyung Choi, Eui Sup Lee, Soo Young Choi &Kyuhyung Han
Cooperative transcriptional activation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 genes by nuclear receptors including Liver-X-Receptor. BMB Report 46, 322-327 (2013)
- M.J.Kim, D.W.Kim, J.H.Park, S.J.Kim, C.H.Lee, J.I.Yong, E.J.Ryu, S.B.Cho, H.J.Yeo, J.Hyeon, S.W.Cho, D.S.Kim, O.Son, J.Park, K.H.Han, Y.S.Cho, W.S.Eum, S.Y.Choi
PEP-1-SIRT2 inhibits inflammatory response and oxidative stress-induced cell death via expression of antioxidant enzymes in murine macrophages. Free Radical Biology &Medicine 63, 432-445 (2013)
- S.C.Ha, A.R.Han, D.W.Kim, E.A.Kim, D.S.Kim, S.Y.Choi, and S.W.Cho Neuroprotective effects of the antioxidant action of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride against ischemic neuronal damage in the brain. BMB Reports 46, 370-375 (2013)
- Eun-A Kim, Jiyoung Choi, A Reum Han, Soo Young Choi, Hoh-Gyu Hahn, and Sung-Woo Cho
Anti-oxidative and anti-inflammatory effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride on glutamate-induced neurotoxicity in rat brain. NeuroToxicology 38, 106-114 (2013)
- Youn GS, Kwon D-J, Ju SM, Choi SY, Park J.
Curcumin ameliorates TNF-α-induced ICAM-1 expression and subsequent THP-1 adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells. BMB Reports. 46, 410-415 (2013)
D.J.Kwon, S.M.Ju, G.S.Yoon, S.Y.Choi and J.Park
Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-<kappa>B and AP-1 activation in RAW 264.7 macrophages. Food and Chemical Toxicology 58, 479-486 (2013)
- S.J.lee, J.H.Kang, S.Y.Choi and O.S.Kwon
PKCδ as a regulator for TGF-β stimulated connective tissue growth factor production in human hepatocarcinoma (HepG2) cells. Biochemical Journal 456, 109-118 (2013)
- Jung Hoon Choi, Dae Won Kim, Dae Young Yoo, Hoon Jae Jeong, Woosuk Kim, Hyo Young Jung, Sung Min Nam, Jong Hwi Kim, Yeo Sung Yoon, Soo Young Choi, In Koo Hwang
Repeated Administration of PEP-1-Cu,Zn-Superoxide Dismutase and PEP-1-Peroxiredoxin-2 to Senescent Mice Induced by D-galactose Improves the Hippocampal Functions. Neurochemical Research 38, 2046-2055 (2013)
- Kim JH, Choi DJ, Jeong HK, Kim J, Kim DW, Choi SY, Park SM, Suh YH, Jou I, Joe EH.
DJ-1 facilitates the interaction between STAT1 and its phosphatase, SHP-1, in brain microglia and astrocytes: a novel anti-inflammatory function of DJ-1. Neurobiology of Diseases 60, 1-10 (2013)
- Eun Hee Ahn, Dae Won Kim, Min Jea Shin, Hyo Sang Jo, Seon Ae Eom, Duk-Soo Kim, Eun Young Park, Jong Hoon Park, Sung-Woo Cho, Jinseu Park, Won Sik Eum, Hyun Sook Hwang, Soo Young Choi
Fenobam promoted the neuroprotective effect of PEP-1-FK506BP following oxidative stress through increasing its transduction efficiency. BMB Reports 46, 561-566 (2013)
- J.J.An,. W.S.Eum, H.S.Kwon, J.S.Koh, S.Y.Lee, J.H.Baek, Y.J.Cho, D.W.Kim, K.H.Han, J. Park, S.H.Jang and S.Y.Choi
Protective effects of skin permeable EGF and FGF1 against ultraviolet-induced skin damage and human skin wrinkles. Journal of Cosmetic Dermatology 12(4), 287-295 (2013)
- S.H.Lee, D.W.Kim, H.R.Kim, S.J.Woo, S.M.Kim, H.S.Jo, S.G.Jeon, S.W. Cho, J.H.Park, M.H.Won, J.Park, W.S.Eum and S.Y.Choi
Anti-inflammatory effects of transduced Tat-Annexin protein on ovalbumin-induced airway inflammation in a mouse model of asthma. Biochemical Biophysical Research Communication 417, 1024-1029 (2012)
- J.E.Kim, H.J.Ryu, S.Y.Choi and T.C.Kang
Tumor necrosis factor-α-mediated threonine 435 phosphorylation of p65 nuclear factor-κB subunit in endothelial cells induces vasogenic edema and neutrophil infiltration in the rat piriform cortex following status epilepticus. Journal of Neuroinflammation 9, 6-18 (2012)
- D.W.Kim, H.S.Hwang, D.S.Kim, S.H.Sheen, D.H.Heo, G.Hwang, S.H.Kang, H.Y. Kweon, Y.Y.Jo, S.W.Kang, K.G.Lee, J.Park, W.S.Eum, Y.J.Cho, S.Y.Choi
Enhancement of Anti-Inflammatory Activity of PEP-1-FK506 Binding Protein by Silk Fibroin Peptide. Journal of Microbiology and Biotechnology 22, 494-500 (2012)
- Sung Mi Ju, Ah Ra Goh, Dong-Joo Kwon, Gi Soo Youn, Hyung-Joo Kwon, Yong
Soo Bae, Soo Young Choi, and Jinseu Park
Extracellular HIV-1 Tat induces human beta-defensin-2 production via NF-kappaB/AP-1 dependent pathways in human B cells. Molecules and Cells 33, 335-341 (2012)
- H.J.Jeong, D.W.Kim, S.J.Woo, H.R.Kim, S.M.Kim, H.S Jo, M.Park, D.S.Kim, O.S.Kwon, I.K.Hwang, K.H.Han, J.Park, W.S.Eum, S.Y.Choi
Transduced Tat-DJ-1 Protein Protects against Oxidative Stress-Induced SH-SY5Y Cell Death and Parkinson Disease in a Mouse Model. Molecules and Cells 33, 471-478 (2012)
Park JH, Lee CH, Yan BC, Ahn JH, Lee YJ, Park CW, Cho JH, Choi SY, Lee YL, Won MH, Lee HY.
Changes in ribosomal protein S3 immunoreactivity and its protein levels in the gerbil hippocampus following subacute and chronic restraint stress. Neurochemical Research 37, 1428-1435 (2012)
- Lee HY, Park JH, Lee CH, Yan B, Ahn JH, Lee YJ, Park CW, Cho JH, Choi SY, Won MH.
Changes of ribosomal protein S3 immunoreactivity and its new expression in microglia in the mice hippocampus after lipopolysaccharide treatment. Cellular and Molecular Neurobiology 32, 577-586 (2012)
- Yoo DY, Shin BN, Kim IH, Kim DW, Yoo KY, Kim W, Lee CH, Choi JH, Yoon YS, Choi SY, Won MH, Hwang IK.
Effects of sensitive to apoptosis gene protein on cell proliferation, neuroblast differentiation, and oxidative stress in the mouse dentate gyrus. Neurochemical Research 37, 495-502 (2012)
- Seong KM, Jung SO, Kim HD, Kim HJ, Jung YJ, Choi SY, and Kim J.
Yeast ribosomal protein S3 possesses a β-lyase activity on damaged DNA. FEBS Letters 586, 356-361, (2012)
- S.H.Lee, D.W.Kim, S.A.Eom, S.Y.Jun, M.Park, D.S.Kim, H.J.Kwon, H.Y.Kwon, K.H.Han, J.Park, H.S.Hwang, W.S.Eum and S.Y.Choi
Suppression of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin inflammation in mice by transduced Tat-Annexin protein. BMB Reports 45, 354-359 (2012)
- E.J.Sohn, D.W.Kim, M.J.Kim, H.J.Jeong, M.J.Shin, E.H.Ahn, S.W.Kwon, Y.N.Kim, D.S.Kim, K.H.Han, J.Park. H.S.Hwang, W.S.Eum, S.Y.Choi
PEP-1-metallothionein-III protein ameliorates the oxidative stress-induced neuronal cell death and brain ischemic insults. Biochimica Biophysica Acta (General Subject) 1820, 1647-1655 (2012)
- Y.P.Lee, D.W.Kim, H.W.Kang, J.H.Hwang, H.J.Jeong, E.J.Sohn, M.J.Kim, E.H.Ahn, M.J.Shin, D.S.Kim, T.C.Kang, O.S. Kwon, S.W.Cho, J.Park, W.S.Eum and S.Y.Choi
PEP-1-heat shock protein 27 protects from neuronal damage in cells and in a Parkinson’s disease mouse model. FEBS Journal 279, 1929-1942 (2012)
- J.Y.Lee, S,Y,Choi, T,H,Oh, and T,Y. Yune
17β-Estradiol Inhibits Apoptotic Cell Death of Oligodendrocytes by Inhibiting RhoA-JNK3 Activation after Spinal Cord Injury. Endocrinology 153, 3815-3827 (2012)
- Eun-A Kim, Seung-Ju Yang, Soo Young Choi, Woo Je Lee, and Sung-Woo Cho
Inhibition of glutamate dehydrogenase and insulin secretion by KHG26377 does not involve ADP-ribosylation by SIRT4 or deacetylation by SIRT3. BMB Reports 45, 458-463 (2012)
- D.S.Kim, E.J.Sohn, D.W.Kim, Y.N.Kim, S.A.Eom, G.H.Yoon, S.W.Cho, S.H.Lee, H. S.Hwang, Y.S.Cho, J.Park,. W.S.Eum and S.Y.Choi
PEP-1-p18 prevents neuronal cell death via the inhibition of oxidative stress and Bax expression. BMB Reports 45, 532-537 (2012)
- D.Kim, M.C.Park, B.KPark, S.Kwon, J.H.Choi, H.J.Kim, S.Y.Choi, J.Park, Y.Lee and H.J.Kwon
Differential expression of cell surface markers in response to 2,4-dinitrofluorobenzene in RAW 264.7 and primary immune cells. BMB Reports 45, 538-543 (2012)
- M.J.Kim, D.W.Kim, H.J.Jeong, E.J.Sohn, M.J.Shin, E.H. Ahn, S.W.Kwon, Y.N.Kim, D.S.Kim, J.Park, W.S.Eum, H.S.Hwang and S.Y.Choi
Tat-Frataxin protects dopaminergic neuronal cells against MPTP-induced toxicity in a mouse model of Parkinson’s disease. Biochimie 94, 2448-2456 (2012)
- Dong-Joo Kwon, Young-Soo Bae, Sung Mi Ju, Ah Ra Goh, Gi Soo Youn, Soo Young Choi, and Jinseu Park
Casuarinin suppresses TARC/CCL17 and MDC/CCL22 production via blockade of NF-<kappa>B and STAT1 activation in HaCaT cells. Biochemical Biophysical Research Communication 417, 1254-1259 (2012)
- D.Y.Yoo, B.N.Shin, I.H.Kim, W.Kim, D.W.Kim, K.Y.oo, J.H.Choi, C.H.Lee, Y.S.Yoon, S.Y.Choi, M.H.Won, I.K.Hwang
Effects of Cu,Zn-Superoxide Dismutase on Cell Proliferation and Neuroblast Differentiation in the Mouse Dentate Gyrus. Neurochemical Research 37, 261-267 (2012)
- Kim W, Kim DW, Yoo DY, Chung JY, Hwang IK, Won MH, Choi SY, Jeon SW, Jeong JH, Hwang HS, Moon SM.
Neuroprotective Effects of PEP-1-Cu,Zn-SOD against Ischemic Neuronal Damage in the Rabbit Spinal Cord. Neurochemical Research 37, 307-313 (2012)
- H.J.Son, S.C.Ha, E.Y.Hwang, E.A.Kim, J.Y.Ahn, S.Y.Choi and S.W.Cho
Roles of cysteine residues in the inhibition of human glutamate dehydrogenase by palmitoyl-CoA. BMB Reports 45, 707-712 (2012)

Others

Scientific Awards

- 1996, 2004 Excellence Science and Technology Awardee from Korean Association of Science and Technology

- 2001 Excellence Science and Technology Awardee from President of Republic of Korea

- 2005 Excellence Science and Technology Awardee from Moon-hwa Broadcasting Company

- 2011 Kangwon Cultural Awardee in the field of Academic Performances and Scientific achievement from President of Kangwon Province

- 2011 Donggok Awardee in the field of Academic Performances and Scientific achievement

- 2013 Excellent Patent Awardee from Administration for Small- and Medium industry of Republic of Korea

- 2015 Moo Sa Awardee from Korean Society of Biochemistry and Molecular Biology

 

Research fields

- Biochemistry (Protein Biochemistry, Neurochemistry)

- Protein Transduction Technology and Protein Therapy

- Development of Protein transduction Technology for Clinical Therapy of Human Diseases

- Development of protein therapy by transduction of therapeutic protein for various human diseases(Aging, Cancer, Neronal disease, Genetic diseases, Diabetes, Stroke etc…)

 

Societies

- The Korean Society for Biochemistry and Molecular Biology

- The Korean Society for Molecular Biology and Cell Biology

- The Korean Society for Brain and Neural Science

- The Korean Society for Genetics

박진서
  • Field

  • Name

    Korean Park, Jin-seo

  • Title

    Professor

  • Office

    The Department of Biomedical Science, The College of Natural Sciences 8411

  • Tel

    033-248-2116

  • email

Educational background

1987 ~ 1992 University of Alabama at Birmingham, USA (Ph.D-Microbiology)
1981 ~ 1983 Korea Advanced Institute of Science and Technology (Master of Science - The Department of Biotechnology)
1983 ~ 1987 Yonsei University (Bachelor of Science - Food Engineering)

 

Major careers

2013 ~ present Dean of The College of Natural Sciences
2006 ~ 2013 BK Head of the Department of Biomedical Science
2012 ~ 2013 Dean of the Department of Biomedical Science
2009 ~ 2012 Director of Research
2006 ~ 2012 Director of Industry-Academia Cooperation
2001 ~ 2002 Visiting Professor, Dept. of Cell Biology, University of Alabama at Birmingham, USA
1994 ~ 현재Assistant Professor, Associate Professor, Professor, Dept. of Biomedical Science, College of Natural Sciences, Hallym University, Korea
1992 ~ 1994 Post-Doctoral Fellow, Harvard Medical School, USA

 

Studies & Books

■ Theses
주저자 : 제1저자, 공동저자(교신), 단독
- Curcumin ameliorates TNF-α-induced ICAM-1 expression and subsequent THP-1 adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells[BMB Reports, SCI급, 공동(교신), 2013] 
- Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages[Food and Chemical Toxicology, SCI급, 공동(교신), 2013] 

 

공동저자 : 공동저자(참여)
- Fenobam promoted the neuroprotective effect of PEP-1-FK506BP following oxidative stress by increasing its transduction efficiency[BMB Reports, SCI급, 공동(참여), 2013] 
- Antitumor activity of methyl gallate by inhibition of focal adhesion formation and Akt phosphorylation in glioma cells[BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, SCI급, 공동(참여), 2013] 
- Transduced PEP-1-FK506BP ameliorates corneal injury in Botulinum toxin A-induced dry eye mouse model[BMB REPORTS, SCI급, 공동(참여), 2013] 
- PEP-1-ribosomal protein S3 protects dopaminergic neurons in an MPTP-induced Parkinson`s disease mouse model[FREE RADICAL BIOLOGY AND MEDICINE, SCI급, 공동(참여), 2013] 
- Transduced Tat-glyoxalase protein attenuates streptozotocin-induced diabetes in a mouse model[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, SCI급, 공동(참여), 2013] 
- PEP-1-SIRT2 inhibits inflammatory response and oxidative stress-induced cell death via expression of antioxidant enzymes in murine macrophages[FREE RADICAL BIOLOGY AND MEDICINE, SCI급, 공동(참여), 2013] 
- TPA로 유도된 마우스 귀 부종 동물모델에서 소목추출물의 항염증 효과[한국식품영양과학회지, SCI급, 공동(참여), 2013] 
- Protective effects of skin permeable EGF and FGF1 against ultraviolet-induced skin damage and human skin wrinkles[Journal of Cosmetic Dermatology, SCI급, 공동(참여), 2013] 

Others

■ Major Research Topics
- Pathogenesis of AIDS by HIV, Development of therapeutic tools using protein transduction technology, Development of therapeutic materials against inflammatory diseases 


■ Academy Activity
- The Korean Society of Virology 
- The Korean Society for Biochemistry and Molecular Biology 
- The Korean Society for Molecular Biology and Cell Biology 

한규형
  • Field

  • Name

    Korean Han, Kyu-hyung

  • Title

    Professor

  • Office

    The Department of Biomedical Science, The College of Natural Sciences 8401

  • Tel

    033-248-2115

  • email

Educational background

1986 ~ 1992 Columbia University, USA (Ph.D-Department of Biology)

1981 ~ 1984 Seoul National University (Master of Science - Department of Microbiology)

1977 ~ 1981 Seoul National University (Bachelor of Science - Department of Microbiology)

Major careers

2013 ~ present Head professor of the Pre-Med Cooperative Major Course

2009 ~ 2011 Dean of the Department of Biomedical Science

2005 ~ 2009 Director of the Biotechnology Research Center

1993 ~ present Assistant Professor, Associate Professor, Professor, Dept. of Biomedical Science, College of Natural Sciences, Hallym University, Korea

1992 ~ 1993 Post-Doctoral Fellow, Cold Spring Harbor Laboratory, USA

Studies & Books

■ Theses
주저자 : 제1저자, 공동저자(교신), 단독
- Cooperative transcriptional activation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 genes by nuclear receptors including Liver-X-Receptor[BMB Reports, SCI급, 공동(교신), 2013]


공동저자 : 공동저자(참여)
- Transduced Tat-glyoxalase protein attenuates sterptozotocin-induced diabetes in a mouse model[Biochemical and Biophysical Research Communications, SCI급, 공동(참여), 2013]
- PEP-1-SIRT2 inhibits inflammatory response and oxidative stress-induced cell death via expression of antioxidant enzymes inmurinemacrophages[Free Radical Biology and Medicine, SCI급, 공동(참여), 2013]
- Antitumor activity of methyl gallate by inhibition of focal adhesion formation and Akt phosphorylation in glioma cells[Biochimica et Biophysica Acta, SCI급, 공동(참여), 2013]
- Protective effects of skin permeable EGF and FGF1 against ultraviolet-induced skin damage and human skin wrinkles[Journal of Cosmetic Dermatology, SCI급, 공동(참여), 2013] 

Others

■ Major Research Topics
- Transcriptional gene regulation, Gene regulation by siRNA


■ Academy Activity
- The Korean Society for Molecular Biology and Cell Biology


■ Awards
- Award of SME Minister (2011)
- Status of Benefit of External Research Fund (Based on research director)

조윤신
  • Field

  • Name

    Korean Cho, Yoon-shin

  • Title

    Professor

  • Office

    The Department of Biomedical Science, The College of Natural Sciences 8407

  • Tel

    033-248-2111

  • email

Educational background

1996 ~ 2001 Major in Molecular Biology, University of Illinois (Doctor)

1993 ~ 1996 Major in Microbiology, University of Wisconsin, U.S. (Master)

1984 ~ 1986 Major in Biology, Sogang University (Master)

1980 ~ 1984 Major in Biology, Sogang University (Bachelor)

Major careers

2013 ~ present Leader of the BK21 Plus Business Team, Hallym University

2013 ~ present The Department of Biomedical Science, Hallym University

2013 ~ present Member of the Evaluation and Management Expert Committee of Healthcare Technology, Korea Centers for Disease Control and Prevention

2013 ~ present Member of the Review Committee of Materials and Resources Utilization, Korea Centers for Disease Control and Prevention

2012 ~ present Expert member of the Life Science Group, the National Research Foundation of Korea

2012 ~ present Leading Scientist of the Korean Academy of Science and Technology

2012 ~ 2013 Head professor of the Pre-Med Cooperative Major Course

2012 ~ present Professor of the Department of Biomedical Science, The College of Natural Sciences, Hallym University

2009 ~ 2011 Health Researcher of the Dielectric Center, the Korea National Institute of Health, the Korea Centers for Disease Control and Prevention

2006 ~ 2009 Chief researcher of the Dielectric Center, the Korea National Institute of Health, the Korea Centers for Disease Control and Prevention

2004 ~ 2006 Research Professor of the Department of Life Science, Hanyang University

2001 ~ 2004 Postdoctoral researcher of Medical School, University of Pennsylvania, U.S.

1989 ~ 1991 Full-time Assistant of the Department of Genetic Engineering, Hallym University

Studies & Books

■ Theses
주저자 : 제1저자, 공동저자(교신), 단독
- Genotype instability during long-term subculture of lymphoblastoid cell lines[JOURNAL OF HUMAN GENETICS, SCI급, 공동(교신), 2013]
- New susceptibility loci in MYL2, C12orf51 and OAS1 associatedwith 1-h plasma glucose as prediposing risk factors for type 2 diabetes in the Korean population[JOURNAL OF HUMAN GENETICS, SCI급, 공동(교신), 2013]


공동저자 : 공동저자(참여)
- Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders[NATURE GENETICS, SCI급, 공동(참여), 2013]
- Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India[DIABETES, SCI급, 공동(참여), 2013]
- Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci[HYPERTENSION, SCI급, 공동(참여), 2013]
- Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4[DIABETOLOGIA, SCI급, 공동(참여), 2013]
- Transduced Tat-glyoxalase protein attenuates streptozotocin-induced diabetes in a mouse model[BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, SCI급, 공동(참여), 2013]
- PEP-1-SIRT2 inhibits inflammatory response and oxidative stress-induced cell death via expression of antioxidant enzymes in murine macrophages[FREE RADICAL BIOLOGY AND MEDICINE, SCI급, 공동(참여), 2013]
- Hwang JY, Lee SH, Go MJ, Kim BJ, Kou I, Ikegawa S, Guo Y, Deng HW, Raychaudhuri S, Kim YJ, Oh JH, Kim Y, Moon S, Kim DJ, Koo H, Cha MJ, Lee MH, Yun JY, Yoo HS, Kang YA, Meta-analysis identifies a MECOM gene as a novel predisposing factor of osteoporotic fracture[JOURNAL OF MEDICAL GENETICS, SCI급, 공동(참여), 2013] 교외 연구비 수혜현황 (연구책임자 기준) 

Others

■ Research

- Korea Genome Organization

- Society for Biochemistry and Molecular Biology

이근욱
  • Field

  • Name

    Korean Lee, Geun-wook

  • Title

    Professor

  • Office

    The Department of Biomedical Science, The College of Natural Sciences 8411

  • Tel

    033-248-2113

  • email

Educational background

- 2005 The Department of Biochemistry, Yonsei University (Doctor of Science)
- 1997 The Department of Biochemistry, Yonsei University (Master of Science)
- 1995 The Department of Biochemistry, Yonsei University (Bachelor of Science)

 

Major careers

2014 ~ present Assistant professor of the Department of Biomedical Science, Hallym University
2013 ~ 2014 The Severance Biomedical Science Institute, the College of Medicine, Yonsei University (Research Professor)
2011 ~ 2013 Department of Pathology, Microbiology &Immunology, Vanderbilt University (Research Instructor)
2006 ~ 2011 Department of Pathology, Microbiology &Immunology, Vanderbilt University (Research Fellow)
2005 ~ 2006 The Institute for Medical Sciences, Hallym University (Research Lecturer)

 

Studies & Books

■ Theses
주저자 : 제1저자, 공동저자(교신), 단독
- Lee, K., Heffington, L., Jellusova, J., Nam, K.T., Raybuck, A., Cho, S.H., Rickert, R., and Boothby, M. (2013) Requirement for Rictor in homeostasis and function of mature B lymphoid cells. Blood. 122: 2369-2379. 
- Lee, K., Boyd, K.L. Parekh, D.V., Kehl-Fie, T.E., Baldwin, H.S., Brakebusch, C., Skaar, E.P., Boothby, M. and Zent, R. (2013) Cdc42 promotes host defenses against fatal infection. Infect. Immun. 81:2714-2723.


공동저자 : 공동저자(참여)
- McGuire, V.A., Gray, A., Monk, C.E., Santos, S.G., Lee, K., Aubareda, A., Crowe, J., Ronkina, N., Schwermann, J., Batty, I.H., Leslie, N.R., Dean, J.L.E., O’Keefe, S.J., Boothby, M., Gaestel, M., and Arthur, J.S. (2013) Crosstalk between Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling. Mol. Cell. Biol. 33: 4152-4156. 
- Williams, C.L., Schilling, M., Cho, S.H., Lee, K., Wei, M., Aditi, and Boothby, M. (2013) STAT4 and T-bet are required for the plasticity of IFN-γ expression across Th2 ontogeny and influence changes in Ifng promoter DNA methylation. J. Immunol. 191:678-687. 
- Rosborough, B.R., Raïch-Regué D., Matta, B.M., Lee, K., Gan, B., DePinho, R.A., Hackstein, H., Boothby, M., Turnquist, H.R., and Thomson, A.W. (2013) Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1 and regulatory T cell induction. Blood. 121:3619-3630

Others

■ Major Research Topics
- mTOR signaling and lymphocyte function 
- mTOR signaling and leukemia development 


■ Academy Activity
- American Association of Immunologist 
- 대한면역학회